HIV Survivor Timothy Ray Brown Dies After Cancer Relapse

LONDON, KOMPAS.com – Timothy Ray Brown died in California after relapsing with cancer, his partner said.

Timothy Ray Brown was the first person known to have been cured of the AIDS-causing virus following a unique type of bone marrow transplant undergone in Berlin.

It was through the procedure that Brown, born on March 11, 1966, was given the moniker the ‘Berlin Patient’ during which his human immunodeficiency viruses were eradicated in Germany in 2007.

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"It is with great sadness that I announce that Timothy passed away ... this afternoon surrounded by myself and friends, after a five-month battle with leukemia," his partner Tim Hoeffgen said in a post on Facebook.

The American's case fascinated and inspired a generation of HIV doctors as well as patients infected with the virus that causes AIDS, offering a glimmer of hope that one day a cure will be found that eventually ends the AIDS pandemic.

Adeeba Kamarulzaman, president of the International AIDS Society, said he would mourn Brown "with a profoundly heavy heart".

"We owe Timothy and his doctor, Gero Huetter, a great deal of gratitude for opening the door for scientists to explore the concept that a cure for HIV is possible," said Kamarulzaman, who is also a Professor of Medicine and Infectious Diseases at Malaya University.

Brown was diagnosed with HIV in 1995 while living in the German capital, and in 2006 was also diagnosed with a type of blood cancer known as acute myeloid leukemia.

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While Brown remained clear of HIV for more than a decade after being treated, he had suffered a relapse of leukemia in the past year.

His doctors said the blood cancer had spread to his spine and brain, and he had recently been in hospice care in his home town of Palm Springs, California.

For Huetter, the German doctor caring for the "Berlin Patient" in 2007, Brown's case was a shot in the dark.

The treatment involved the destruction of Brown's immune system and the transplanting of stem cells with a gene mutation called CCR5 that resists HIV.

Only a tiny proportion of people — most of them of northern European descent — have the CCR5 mutation that makes them resistant to the AIDS-causing virus.