Baca berita tanpa iklan. Gabung Kompas.com+

HIV Survivor Timothy Ray Brown Dies After Cancer Relapse

September 30, 2020, 10.17 PM

LONDON, KOMPAS.com – Timothy Ray Brown died in California after relapsing with cancer, his partner said.

Timothy Ray Brown was the first person known to have been cured of the AIDS-causing virus following a unique type of bone marrow transplant undergone in Berlin.

It was through the procedure that Brown, born on March 11, 1966, was given the moniker the ‘Berlin Patient’ during which his human immunodeficiency viruses were eradicated in Germany in 2007.

Read also: Colon Cancer Claims Life of “Black Panther” Star Chadwick Boseman

"It is with great sadness that I announce that Timothy passed away ... this afternoon surrounded by myself and friends, after a five-month battle with leukemia," his partner Tim Hoeffgen said in a post on Facebook.

The American's case fascinated and inspired a generation of HIV doctors as well as patients infected with the virus that causes AIDS, offering a glimmer of hope that one day a cure will be found that eventually ends the AIDS pandemic.

Adeeba Kamarulzaman, president of the International AIDS Society, said he would mourn Brown "with a profoundly heavy heart".

"We owe Timothy and his doctor, Gero Huetter, a great deal of gratitude for opening the door for scientists to explore the concept that a cure for HIV is possible," said Kamarulzaman, who is also a Professor of Medicine and Infectious Diseases at Malaya University.

Brown was diagnosed with HIV in 1995 while living in the German capital, and in 2006 was also diagnosed with a type of blood cancer known as acute myeloid leukemia.

Read also: America in Mourning Following Death of Justice Ruth Bader Ginsburg

While Brown remained clear of HIV for more than a decade after being treated, he had suffered a relapse of leukemia in the past year.

His doctors said the blood cancer had spread to his spine and brain, and he had recently been in hospice care in his home town of Palm Springs, California.

For Huetter, the German doctor caring for the "Berlin Patient" in 2007, Brown's case was a shot in the dark.

The treatment involved the destruction of Brown's immune system and the transplanting of stem cells with a gene mutation called CCR5 that resists HIV.

Only a tiny proportion of people — most of them of northern European descent — have the CCR5 mutation that makes them resistant to the AIDS-causing virus.

Read also: Gallup Poll Shows Migrant Acceptance on the Decline Globally

This and other factors made the treatment the "Berlin Patient" had expensive, complex, and highly risky.

Most experts say it could never become a way to cure all HIV patients since many of them would risk death from the procedure itself.

More than 37 million people worldwide are currently infected with HIV, and the AIDS pandemic has killed about 35 million people since it began in the 1980s.

Read also: Women Globally Lack Access to Contraceptives and Abortions during Lockdown

Medical advances over the past three decades have led to the development of drug combinations known as antiretroviral therapies that can keep the virus in check, allowing many HIV positive people to live with the virus for years.

A second HIV patient, Adam Castillejo, who was known as "the London patient" until he revealed his identity this year, is also thought to be in remission from HIV after having a transplant in 2016 similar to the one Timothy Ray Brown had.

"Although the cases of Timothy and Adam are not a viable large-scale strategy for a cure, they do represent a critical moment in the search for an HIV cure," said Sharon Lewin, a Professor and HIV Specialist at Australia's Doherty Institute.

She said Timothy Ray Brown was "a champion and advocate for keeping an HIV cure on the political and scientific agenda", and added:

"It is the hope of the scientific community that one day we can honor his legacy with a safe, cost-effective and widely accessible strategy to achieve HIV remission and cure."

(Writer: Kate Kelland | Editors: Gareth Jones, Nick Macfie)

Source: https://www.reuters.com/article/health-aids-cure-death/worlds-first-patient-cured-of-hiv-dies-after-cancer-returns-idINKBN26L19M 

Simak breaking news dan berita pilihan kami langsung di ponselmu. Pilih saluran andalanmu akses berita Kompas.com WhatsApp Channel : https://www.whatsapp.com/channel/0029VaFPbedBPzjZrk13HO3D. Pastikan kamu sudah install aplikasi WhatsApp ya.



Comment wisely and responsibly. Comments are entirely the responsibility of the commentator as regulated in the ITE Law
Report
Thank You! We have received your report. We will remove comments that conflict with the Community Guidelines and the ITE Law.

More Headlines

News
April 14, 2023, 12.38 PM

Indonesia Detects New Covid Arcturus Variant

Baca berita tanpa iklan. Gabung Kompas.com+
Baca berita tanpa iklan. Gabung Kompas.com+

MOST POPULAR

Baca berita tanpa iklan. Gabung Kompas.com+
Baca berita tanpa iklan. Gabung Kompas.com+
Close Ads
Oke